Amikacin (Amikin) - A guide to use

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Amikacin (Amikin) - A guide to use

Post  Admin on Sat Apr 21, 2012 6:11 pm

Amikacin

Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth.

Amikacin is most often used for treating severe, infections with multidrug resistant Gram negative bacteria such as Pseudomonas aeruginosa.

Side effects of amikacin are similar to other aminoglycosides; renal failure as a result of overdosing. Hydration levels are thus vital.

Dosage

Amikacin (amiglyde sulfate) 5 mg/kg IM, then 2.5 mg/kg IM q 72 hr Highly nephrotoxic - give with SC/IC fluids
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